Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis
Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis
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DOI：
10.1007/s004150050206
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发表时间：
1998-04-01
影响因子：
6
通讯作者：
Dengler, R
中科院分区：
文献类型：
--
作者：
Munte, TF;Troger, MC;Dengler, R
对14例肌萎缩性侧索硬化症（ALS）患者和14例对照者进行3种不同视觉实验的诱发电位记录。对照受试者的诱发电位（EPs）在99 ~ 140 ms （P1）范围内呈初始阳性。这一成分在ALS患者的组平均和个体EPs中均不存在。由于已知P1起源于下枕颞区，这一发现为ALS包括视觉区在内的皮质受累提供了电生理学证据。
Evoked potentials were recorded in three different visual experiments in 14 patients with amyotrophic lateral scierosis (ALS) and 14 matched control subjects. Control subjects' evoked potentials (EPs) were characterized by an initial positivity in the 99-140 ms range (P1) at the temporo-occipital site. This component was absent from the group average of the ALS patients as well as the individual patients' EPs. As the P1 is known to emanate from inferior occipito-temporal areas, this finding provides electrophysiological evidence for a cortical involvement in ALS including visual areas.