Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections
Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections
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DOI：
10.1016/j.ijid.2020.07.034
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发表时间：
2020-10-01
影响因子：
8.4
通讯作者：
Fukunaga, Koichi
中科院分区：
文献类型：
--
作者：
Nakagawara, Kensuke;Masaki, Katsunori;Fukunaga, Koichi
本研究利用周期阈值(Ct)qPCR值，对57例无症状/轻度SARS-CoV-2感染患者的症状与病毒清除之间的关系进行了研究。与无嗅觉/味觉障碍(OTDS)的患者相比，有嗅觉/味觉障碍(OTDS)的患者表现出较低的qPCRct值和较长的qPCR阴性时间，这表明OTDS与高病毒载量有关。(C)2020年提交人(S)。爱思唯尔有限公司代表国际传染病学会出版。
This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infection. Patients with olfactory/taste disorders (OTDs) exhibited lower qPCR Ct values and longer time to negative qPCR than those without OTDs, suggesting an association between OTDs and high viral burden. (c) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.