Understanding the Short- and Long-Term Respiratory Outcomes of Prematurity and Bronchopulmonary Dysplasia
Understanding the Short- and Long-Term Respiratory Outcomes of Prematurity and Bronchopulmonary Dysplasia
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DOI：
10.1164/rccm.201412-2142pp
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发表时间：
2015-07-15
影响因子：
24.7
通讯作者：
Moore, Paul E.
中科院分区：
文献类型：
--
作者：
Islam, Jessica Y.;Keller, Roberta L.;Moore, Paul E.
支气管肺发育不良（BPD）是一种与早产相关的慢性呼吸道疾病，主要影响胎龄小于28周的婴儿。BPD是早产儿经历的最常见的严重并发症，仅在美国每年就有8，000多名新诊断的婴儿。鉴于BPD早产存活者的数量不断增加，改善BPD婴儿长期呼吸道发病率的知识现状是当务之急。我们对已发表的文献进行了全面的回顾，以分析和巩固目前对BPD影响的认识，这些影响在生命的特定阶段，包括婴儿期，儿童期和成年期。在这篇综述中，我们讨论了被诊断为患有这种疾病的婴儿的短期和长期呼吸结果，并强调了改善这些患者的早期和终身管理所需的知识差距。
Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease associated with premature birth that primarily affects infants born at less than 28 weeks' gestational age. BPD is the most common serious complication experienced by premature infants, with more than 8,000 newly diagnosed infants annually in the United States alone. In light of the increasing numbers of preterm survivors with BPD, improving the current state of knowledge of long-term respiratory morbidity for infants with BPD is a priority. We undertook a comprehensive review of the published literature to analyze and consolidate current knowledge of the effects of BPD that are recognized at specific stages of life, including infancy, childhood, and adulthood. In this review, we discuss both the short-term and long-term respiratory outcomes of individuals diagnosed as infants with the disease and highlight the gaps in knowledge needed to improve early and lifelong management of these patients.