Disappearance of metastatic renal cell carcinoma to the base of the tongue after systemic administration of interferon-alpha.
Disappearance of metastatic renal cell carcinoma to the base of the tongue after systemic administration of interferon-alpha.
复制标题
全身施用干扰素-α后，舌根转移性肾细胞癌消失。
DOI：
10.1159/000474313
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发表时间：
1993
期刊：
影响因子：
23.4
通讯作者：
S. Morinaga
中科院分区：
文献类型：
--
作者：
T. Shibayama;S. Hasegawa;S. Nakamura;M. Tachibana;S. Jitsukawa;A. Shiotani;S. Morinaga
我们报告一位41岁的日本男性，在右肾根治性切除术后34个月出现肺、骨、淋巴结及舌根转移。全身应用人类淋巴母细胞干扰素（IFN）一个月后，舌根转移完全消失，而其他转移灶的大小和数量均增加。虽然IFN-α对转移到舌根的肾细胞癌的真实作用仍然未知，但我们的病例表明，舌可能是IFN-α治疗的敏感部位。
We describe a 41-year-old Japanese man with metastases of the lung, bone, lymph nodes and the base of the tongue 34 months after right radical nephrectomy. One month after systemic administration of human lymphoblastoid interferon (IFN), the metastasis to the base of the tongue completely disappeared, while other metastases increased both in size and number. Though the true effect of IFN-alpha on the metastatic renal cell carcinoma to the base of the tongue is still unknown, our case indicates that the tongue is a possible sensitive site to IFN-alpha therapy.