Effect of menses on clearance of Y-chromosome in vaginal fluid: implications for a biomarker of recent sexual activity.
Effect of menses on clearance of Y-chromosome in vaginal fluid: implications for a biomarker of recent sexual activity.
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DOI：
10.1097/olq.0b013e3181b5f15d
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发表时间：
2010-01
影响因子：
3.1
通讯作者：
Zenilman JM
中科院分区：
文献类型：
--
作者：
Brotman RM;Melendez JH;Smith TD;Galai N;Zenilman JM
自我报告的性行为会受到偏见的影响。我们以前开发了一种聚合酶链反应，用于检测阴道液中的Y染色体序列，作为近期性活动的潜在生物标志物。在这项研究中，我们发现月经导致Y染色体浓度较低，但与非月经样本具有相似的衰减模式。
Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker for recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.