Viral shedding and transmission between hosts determined by reovirus L2 gene.
Viral shedding and transmission between hosts determined by reovirus L2 gene.
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由呼肠孤病毒 L2 基因决定的病毒脱落和宿主之间的传播。
DOI：
10.1126/science.3012780
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Fields,BN
中科院分区：
文献类型：
--
作者：
Keroack,M;Fields,BN
两个呼肠孤病毒分离株(1型朗氏呼肠孤病毒和3型呼肠孤病毒)在新生小鼠产仔之间的传播率不同。它们在胃肠道排泄的病毒数量上也有所不同。随着重组病毒的使用，这些特性被映射到L2基因。因此，呼肠孤病毒的环境传播是一种遗传特性。
Two reovirus isolates (type 1 Lang and type 3 Dearing) differ in their transmissibility between littermates of newborn mice. They also differ in the amounts of virus excreted by the gastrointestinal tract. With the use of reassortant viruses, these properties were mapped to the L2 gene. Thus environmental spread of reovirus is a genetic property.