High/low cortisol reactivity and food intake in people with obesity and healthy weight

High/low cortisol reactivity and food intake in people with obesity and healthy weight
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DOI:
10.1038/s41398-020-0729-6
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发表时间:
2020-01-27
影响因子:
6.8
通讯作者:
Petrowski, Katja
Petrowski, Katja
中科院分区:
医学1区
文献类型:
--
作者:
Herhaus, Benedict;Ullmann, Enrico;Petrowski, Katja

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增加食物摄入量,称为“舒适饮食”,是慢性压力的一种病理性应对机制。压力下的皮质醇反应是压力诱发的饮食行为影响体重指数 (BMI) 的有效预测指标。然而,尚未评估肥胖人群压力下的皮质醇反应性和食物摄入量。本研究的目的是调查在标准化压力诱导和休息条件下,高/低皮质醇反应性对肥胖者和健康体重测试对照者食物摄入的影响。 36 名肥胖男性和女性(BMI:33.00 +/- 3.23kg/m(2))以及 36 名年龄和性别匹配的健康体重对照者(BMI:21.98 +/- 1.81kg/m(2))在特里尔社会压力测试(TSST)中被分为高皮质醇反应者(HCR)和低皮质醇反应者(LCR)。在 TSST 和休息条件后,所有参与者的食物摄入量均记录在标准化实验室膳食中。肥胖 HCR 的食物摄入量显着高于 LCR (t (34)=-2.046,p
Increased food intake, termed "comfort eating", is a pathologic coping mechanism in chronic stress. Cortisol reactivity under stress is a potent predictor of stress-induced eating behavior affecting the body mass index (BMI). However, cortisol reactivity and food intake under stress in people with obesity has not been evaluated. The aim of this study was to investigate the effect of high/low cortisol reactivity on food intake in people with obesity and healthy weight test controls, following standardized stress induction and a resting condition. Thirty-six men and women with obesity (BMI: 33.00 +/- 3.23kg/m(2)), as well as 36 age- and gender-matched healthy weight controls (BMI: 21.98 +/- 1.81kg/m(2)) were categorized into high cortisol reactors (HCR) and low cortisol reactors (LCR) in the Trier Social Stress Test (TSST). Following the TSST and a resting condition, the food intake of all participants was recorded in a standardized laboratory meal. Obese HCR demonstrated a significantly higher food intake than LCR (t (34)=-2.046, p