Utility of childhood BMI in the prediction of adulthood disease: Comparison of national and international references
Utility of childhood BMI in the prediction of adulthood disease: Comparison of national and international references
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DOI：
10.1038/oby.2005.129
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发表时间：
2005-06-01
期刊：
影响因子：
--
通讯作者：
Berenson, GS
中科院分区：
文献类型：
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作者：
Janssen, I;Katzmarzyk, PT;Berenson, GS
Janssen, ian, Peter t. katzmarzyk, sathanur, r. srinivasan, wei chen, Robert m. malina， Claude bouchard和Gerald s. berenson。儿童期BMI在预测成年期疾病中的应用：国内和国际参考文献的比较。科学通报。2005;13:1106-1115。目的：确定美国疾病控制和预防中心（CDC； CDC参考）或国际肥胖工作组（IOTF； IOTF参考）分类儿童肥胖状况的BMI分界点是否更有效地预测未来的健康风险。研究方法和程序：样本（n1709）包括来自Bogalusa心脏研究的4至15岁（基线）男孩和女孩。使用CDC参考和IOTF参考BMI基线分界点确定超重和肥胖状况。然后比较了两种BMI分类系统确定的儿童超重和肥胖预测成年后肥胖和代谢紊乱的能力（经过13至24年的随访）。结果：与儿童期BMI的肥胖分类系统无关，与非超重组相比，超重和肥胖组在青年期出现肥胖和所有代谢紊乱的几率均显著（p < 0.05）升高。儿童超重和肥胖，由CDC参考文献和IOTF参考文献确定。在预测青少年肥胖和代谢紊乱方面具有低敏感性和高特异性。与基于IOTF参考的相应值相比，CDC参考所确定的超重和肥胖的敏感性略高，特异性略低。讨论：儿童期超重和肥胖，由CDC和IOTF BMI分界点确定。是成年早期肥胖和冠心病危险因素的有力预测因子。然而，CDC参考文献和IOTF参考文献的预测能力差异很小。
JANSSEN, IAN, PETER T. KATZMARZYK, SATHANUR, R. SRINIVASAN, WEI CHEN, ROBERT M. MALINA, CLAUDE BOUCHARD, AND GERALD S. BERENSON. Utility of childhood BMI in the prediction of adulthood disease: comparison of national and international references. Obes Res. 2005;13:1106-1115.Objective: To determine whether the U.S. Centers for Disease Control and Prevention (CDC; CDC Reference) or International Obesity Task Force (IOTF; IOTF Reference) BMI cut-off points for classifying adiposity status in children are more effective at predicting future health risk.Research Methods and Procedures: The sample (N 1709) included 4- to 15-year-old (at baseline) boys and girls from the Bogalusa Heart Study. Overweight and obesity status were determined using both the CDC Reference and IOTF Reference BMI cut-off points at baseline. The ability of childhood overweight and obesity, determined from the two BMI classification systems, to predict obesity and metabolic disorders in young adulthood (after a 13- to 24-year follow-up) was then compared.Results: Independently of the classification system employed to determine adiposity based on childhood BMI, the odds of being obese and having all of the metabolic disorders in young adulthood were significantly (p < 0.05) higher in the overweight and obese groups by comparison with the nonoverweight groups. Childhood overweight and obesity, determined by both the CDC Reference and IOTF Reference. had a low sensitivity and a high specificity for predicting obesity and metabolic disorders in young adulthood. Overweight and obesity as determined by the CDC Reference were slightly more sensitive and slightly less specific than the corresponding Values based Oil the IOTF Reference.Discussion: Overweight and obesity during childhood, as determined by both the CDC and IOTF BMI cut-off points. are strong predictors of obesity and coronary heart disease risk factors in young adulthood. The differences in the predictive capacity of the CDC Reference and IOTF Reference are, however, minimal.