Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the US, 2000-2002
Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the US, 2000-2002
复制标题
DOI：
10.2337/diacare.28.7.1599
复制
发表时间：
2005-07-01
期刊：
影响因子：
16.2
通讯作者：
Hill, JO
中科院分区：
文献类型：
--
作者：
Sullivan, PW;Morrato, EH;Hill, JO
目的 - 肥胖和缺乏身体活动是 2 型糖尿病和心血管合并症的既定危险因素。肥胖和健康水平哪个对健康更重要尚存在争议。本研究的目的是确定美国身体活动和体重指数与糖尿病和糖尿病相关心血管合并症患病率的相对关系。研究设计和方法 - 医疗支出小组调查 (MEPS) 是一项针对美国人口的全国代表性调查。从 2000 年到 2002 年，收集了 68,500 名成年人的社会人口特征和健康状况的详细信息。正常体重定义为 BMI 18.5 至 < 25 kg/m(2)，超重 25 至 30 kg/m(2)，肥胖（I 级和 II 级）30 至 < 40 kg/m(2)，以及肥胖（III 级）>= 40 kg/m(2)。体力活动定义为每周 >= 30 分钟 >= 3 天的中度/剧烈活动。 结果 - 无论体力活动如何，罹患糖尿病和糖尿病相关心血管合并症的可能性均随 BMI 的增加而增加，而无论 BMI 为何，患糖尿病和糖尿病相关心血管合并症的可能性均随体力不活动而增加。与正常体重活跃成人相比，正常体重不活跃成人糖尿病的多变量调整比值比（OR）为1.52（95% CI 1.25-1.86），超重不活跃成人为1.65（1.40-1.96）；对于体重正常、不活动的成人，糖尿病和合并高血压的 OR 为 1.71 (1.32-2.19)；对于超重不活动的成人，糖尿病和合并高血压的 OR 为 1.84 (1.47-2.32)。 结论 - 缺乏身体活动和肥胖似乎与糖尿病和糖尿病相关合并症有很强的独立相关性。这些结果支持继续研究这些因素的独立因果性质。
OBJECTIVE - Obesity and physical inactivity are established risk factors for type 2 diabetes and cardiovascular comorbidities. Whether adiposity or fitness level is more important to health is controversial. The objective of this research is to determine the relative associations of physical activity and BMI with the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the U.S.RESEARCH DESIGN AND METHODS - The Medical Expenditure Panel Survey (MEPS) is a nationally representative survey of the U.S. population. From 2000 to 2002, detailed information on sociodemographic characteristics and health conditions were collected for 68,500 adults. Normal weight was defined as BMI 18.5 to < 25 kg/m(2), overweight 25 to : 30 kg/m(2), obese (class I and II) 30 to < 40 kg/m(2), and obese (class III) >= 40 kg/m(2). Physical activity was defined as moderate/vigorous activity >= 30 min >= 3 days per week.RESULTS - The likelihood of having diabetes and diabetes-related cardiovascular comorbidities increased with BMI regardless of physical activity and increased with physical inactivity regardless of BMI. Compared with normal-weight active adults, the multivariate-adjusted odds ratio (OR) for diabetes was 1.52 (95% CI 1.25-1.86) for normal-weight inactive adults and 1.65 (1.40-1.96) for overweight Inactive adults; the OR for diabetes and comorbid hypertension was 1.71 (1.32-2.19) for normal-weight inactive adults and 1.84 (1.47-2.32) for overweight inactive adults.CONCLUSIONS - Both physical inactivity and obesity seem to be Strongly and independently associated With diabetes and diabetes-related comorbidities. These results support continued research investigating the independent causal nature of these factors.