A posteriori respiratory motion gating of dynamic PET images
A posteriori respiratory motion gating of dynamic PET images
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动态 PET 图像的后呼吸运动门控
DOI：
10.1109/nssmic.2003.1352596
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Y. Bizais
中科院分区：
文献类型：
--
作者：
D. Visvikis;O. Barret;T. Fryer;A. Turzo;F. Lamare;C. Cheze Le Rest;Y. Bizais
在成像过程中患者生理运动的存在可能会导致图像质量的显著伪影。提出的校正方法包括通过同时记录外部信号使用门控采集。我们工作的目的是确定在没有任何外部信号的情况下动态获取的PET图像采集后同步的可行性。该技术的原理是基于这样的假设：尽管在同一器官内，运动的幅度可能在像素之间变化，但周期运动的频率是相同的。在这种情况下，后验门控的先决条件是准确估计频率的能力。我们使用NCAT假体和GE Advance PET系统的蒙特卡罗模拟（3D操作模式）进行了模拟研究。在整个呼吸周期中产生了许多NCAT排放和相应的传输帧。0.15、0.45和0.62秒的时间帧用可变计数统计（即模拟的总巧合数的30k、70k和120k）进行模拟。对形成的每一个动态序列，采用不同的roi得到时间活动曲线，并进行傅里叶变换以估计模拟运动的频率。我们能够确定所有三个帧时间持续时间的运动频率（在模拟频率的2%以内）。利用估计的频率，我们能够逐像素地计算运动的幅度和相位，使我们能够重建一个后验门控时间序列。
The presence of patient physiological motion during imaging may cause significant artifacts in image quality. Proposed correction methodologies involve the use of gated acquisitions through simultaneous recording of an external signal. The purpose of our work is to determine the feasibility of post-acquisition synchronization of dynamically acquired PET images in the absence of any external signal. The principle of the technique is based on the assumption that although the amplitude of the motion may vary from pixel to pixel inside the same organ, the frequency of the periodic motion is the same. Under such conditions, the prerequisite for a posteriori gating is the ability to accurately estimate that frequency. We performed simulation studies using the NCAT phantom and a Monte Carlo simulation of the GE Advance PET system (3D mode of operation). A number of NCAT emission and the corresponding transmission frames were generated throughout a respiratory cycle. Time frames of 0.15, 0.45 and 0.62 seconds were simulated with variable count statistics (namely 30k, 70k and 120k of total simulated coincidences). Time activity curves were obtained, for each of the dynamic series formed, using different ROIs and Fourier transform was performed in order to estimate the frequency of the simulated motion. We were able to determine the frequency of motion (within 2% of the simulated frequency) for all three frame time durations evaluated. Using the estimated frequency we were able to calculate on a pixel by pixel basis the amplitude and the phase of the motion, allowing us to reconstruct an a posteriori gated time series.
呼吸门控对肺癌 PET 图像量化的影响。
DOI：
--
发表时间：
2002
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Nehmeh,SadekA;Erdi,YusufE;Ling,CliftonC;Rosenzweig,KennethE;Schoder,Heiko;Larson,SteveM;Macapinlac,HomerA;Squire,OliviaD;Humm,JohnL
通讯作者：
Humm,JohnL