Red cell and platelet transfusions in neonates: a population-based study
Red cell and platelet transfusions in neonates: a population-based study
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DOI：
10.1136/archdischild-2014-307716
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发表时间：
2015-09-01
影响因子：
4.4
通讯作者：
Ford, Jane B.
中科院分区：
文献类型：
--
作者：
Bowen, Jennifer R.;Patterson, Jillian A.;Ford, Jane B.
目的本研究的目的是描述使用红细胞，血小板和交换输血之间的所有新生儿在人口队列，检查随着时间的推移，输血的趋势，并确定输血率在高危新生儿。设计链接的人口为基础的出生和医院的数据从新南威尔士州（NSW），澳大利亚，被用来确定血液制品输血率在第一个28天的生活。结果2001年至2011年，在989491例活产新生儿中，有5326例接受了红细胞、血小板或换血治疗（5.4/1000）。红细胞输血率为4.8/1000，血小板输血率为1.3/1000，换血率为0.3/1000。2001年至2011年的总体输血率保持不变（p=0.27）。在输血的新生儿中，60%为≥ 32周妊娠，7%在没有NICU的医院输血。这些发现需要考虑的输血服务和人员制定新生儿输血指南。
Objectives This study aimed to describe the use of red cells, platelets and exchange transfusions among all neonates in a population cohort, to examine trends in transfusion over time and to determine transfusion rates in at-risk neonates.Design Linked population-based birth and hospital data from New South Wales (NSW), Australia, were used to determine rates of blood product transfusion in the first 28 days of life. The study included all live births >= 23 weeks' gestation in NSW between 2001 and 2011.Results Between 2001 and 2011, 5326 of 989 491 live born neonates received a red cell, platelet or exchange transfusion (5.4/1000 births). Transfusion rates were 4.8 per 1000 for red cells, 1.3 per 1000 for platelets and 0.3 per 1000 for exchange transfusion. Overall transfusion rate remained constant from 2001 to 2011 (p=0.27). Among transfused neonates, 60% were = 32 weeks' gestation and 7% were transfused in hospitals without an NICU. These findings need to be considered by transfusion services and personnel developing neonatal transfusion guidelines.