Cardiovascular CT angiography in neonates and children: Image quality and potential for radiation dose reduction with iterative image reconstruction techniques
Cardiovascular CT angiography in neonates and children: Image quality and potential for radiation dose reduction with iterative image reconstruction techniques
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DOI：
10.1007/s00330-012-2734-5
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发表时间：
2013-05-01
影响因子：
5.9
通讯作者：
Apfaltrer, Paul
中科院分区：
文献类型：
--
作者：
Tricarico, Francesco;Hlavacek, Anthony M.;Apfaltrer, Paul
为了评价低辐射剂量儿科心血管CT血管造影（CTA）的图像质量（IQ），比较图像空间迭代重建（IRIS）和正弦图确认迭代重建（SAFIRE）与滤波反投影（FBP），并估计进一步降低剂量的可能性。用FBP、IRIS和SAFIRE重建数据。对于ECG同步研究，模拟了半剂量图像采集。测量信号噪声并进行IQ分级。IRIS和全剂量SAFIRE的平均绝对和相对图像噪声低于FBP（P < 0.001），而SNR和CNR高于FBP（P < 0.001）。与全剂量和半剂量FBP研究相比，半剂量SAFIRE研究的图像噪声也较低，SNR和CNR较高（P < 0.001）。IRIS、全剂量SAFIRE和半剂量SAFIRE组的IQ评分均高于全剂量FBP组，半剂量SAFIRE组高于半剂量FBP组（P < 0.05）。不进行ECG同步时的中位体重特异性艾德为0.3 mSv，进行ECG同步时为1.36 mSv。半剂量SAFIRE研究的估计艾德为0.68 mSv。IR改善了图像噪声、SNR，在低辐射剂量的儿科CTA中，与FBP相比，CNR和主观智商，并允许进一步降低剂量而不影响诊断智商。儿童有创性心血管CT使用一半传统辐射剂量迭代重建图像质量更高迭代重建技术可以进一步减少儿科心血管CT的辐射。
To evaluate image quality (IQ) of low-radiation-dose paediatric cardiovascular CT angiography (CTA), comparing iterative reconstruction in image space (IRIS) and sinogram-affirmed iterative reconstruction (SAFIRE) with filtered back-projection (FBP) and estimate the potential for further dose reductions.Forty neonates and children underwent low radiation CTA with or without ECG synchronisation. Data were reconstructed with FBP, IRIS and SAFIRE. For ECG-synchronised studies, half-dose image acquisitions were simulated. Signal noise was measured and IQ graded. Effective dose (ED) was estimated.Mean absolute and relative image noise with IRIS and full-dose SAFIRE was lower than with FBP (P < 0.001), while SNR and CNR were higher (P < 0.001). Image noise was also lower and SNR and CNR higher in half-dose SAFIRE studies compared with full-and half-dose FBP studies (P < 0.001). IQ scores were higher for IRIS, full-dose SAFIRE and half-dose SAFIRE than for full-dose FBP and higher for half-dose SAFIRE than for half-dose FBP (P < 0.05). Median weight-specific ED was 0.3 mSv without and 1.36 mSv with ECG synchronisation. The estimated ED of half-dose SAFIRE studies was 0.68 mSv.IR improves image noise, SNR, CNR and subjective IQ compared with FBP in low-radiation-dose paediatric CTA and allows further dose reductions without compromising diagnostic IQ.aEuro cent Iterative reconstruction techniques significantly improve non-invasive cardiovascular CT in children.aEuro cent Using half traditional radiation dose image quality is higher with iterative reconstruction.aEuro cent Iterative reconstruction techniques may allow further radiation reductions in paediatric cardiovascular CT.