Biomechanical measurements in microscopically thin stratum corneum using acoustics

Biomechanical measurements in microscopically thin stratum corneum using acoustics
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DOI:
10.1034/j.1600-0846.2001.70408.x
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发表时间:
2001-11
影响因子:
2.2
通讯作者:
T. Gardner;G. Briggs
T. Gardner;G. Briggs
中科院分区:
医学4区
文献类型:
--
作者:
T. Gardner;G. Briggs

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背景/目标:本研究调查了是否可以开发一种扫描声学显微镜(SAM)来测量皮肤的微观薄外层角质层的机械性能的变化。本文用10 μm厚的人体皮肤薄片,用改进的显微镜测定了各种水溶液试剂对厚度、密度、压缩波速度和弹性常数的影响,并与水作了比较。
Background/aims: This study investigated whether a scanning acoustic microscope (SAM) could be developed to measure changes in the mechanical properties of the microscopically thin external layer of skin, the stratum corneum. The adapted microscope was used to determine the effects of various aqueous reagents, as compared with water, on the thickness, density, compression wave velocity and elastic constant, using 10 μm thin sections of human skin.