ACUTE AND CHRONIC-RENAL-FAILURE IN LIVER-TRANSPLANTATION
ACUTE AND CHRONIC-RENAL-FAILURE IN LIVER-TRANSPLANTATION
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DOI：
10.1159/000185938
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发表时间：
1990-06-01
期刊：
影响因子：
2.5
通讯作者：
PUSCHETT, JB
中科院分区：
文献类型：
--
作者：
MCCAULEY, J;VANTHIEL, DH;PUSCHETT, JB
我们对105例接受肝移植的成人患者急性肾功能衰竭（ARF）的发生率和病因进行了回顾性分析。慢性肾衰竭的患病率也被确定。ARF发生率为94.2%。急性肾小管坏死是ARF的主要原因，死亡率最高。与死亡率增加相关的因素包括：(1)血肌酐峰值bbb30 mg/dl，(2)多次肝移植和(3)需要透析。移植前肾功能衰竭不增加死亡率。在最近的随访中，83%的患者出现了慢性肾衰竭（平均：30.5 +-）。7.9个月)。
We have performed a retrospective review of the incidence and etiologies of acute renal failure (ARF) in 105 adult patients receiving liver transplants. The prevalence of chronic renal failure was also determined. ARF occurred in 94.2% of these patients. Acute tubular necrosis was the leading cause of ARF and was associated with the highest mortality. Factors associated with increased mortality included: (1) peak serum creatinine > 3 mg/dl, (2) multiple liver transplants and (3) the need for dialysis. Pretransplant renal failure did not increase mortality. Chronic renal failure developed in 83% of patients at latest follow-up (mean :30.5 .+-. 7.9 months).