Metalloprotease Peptide Inhibitors: A Semester-Long Organic Synthetic Research Project for the Introductory Laboratory Course.
Metalloprotease Peptide Inhibitors: A Semester-Long Organic Synthetic Research Project for the Introductory Laboratory Course.
复制标题
金属蛋白酶肽抑制剂：一个为期一个学期的实验室入门课程有机合成研究项目。
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Jason K. Pontrello
中科院分区：
文献类型：
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作者：
Jason K. Pontrello
一个学期的研究项目，以合成独特的化合物后，发表的金属蛋白酶肽抑制剂的设计。该研究项目包括传统上在第二学期实验室课程中教授的一组九个有机化学反应，并且程序来自科学文献。课程设计的两个主要目标是：（1）通过研究项目的科学应用提高学生的兴趣;（2）向学生介绍合成有机化学研究经验，以培养这一领域所需的技能。除了探索新化合物的合成，学生阅读有关金属蛋白酶抑制剂的背景综述文章。该项目的设计提供了多年合作的机会，在大学内的不同课程之间，以及不同的学校之间。
A semester-long research project to synthesize unique compounds designed after published metalloprotease peptide inhibitors is presented. The research project encompasses a set of nine organic chemistry reactions traditionally taught in the second semester lab course, and the procedures are derived from scientific literature. The two principle goals of the course design are (1) to enhance student interest through the scientific applications of the research project and (2) to introduce students to a synthetic organic chemistry research experience to develop skills needed in this area. In addition to the exploratory synthesis of novel compounds, students read background review articles about metalloprotease inhibitors. The design of the project provides opportunity for collaboration over multiple years, between different courses within the university, and among different schools.