THE ASSOCIATION BETWEEN BLOOD-PRESSURE, AGE, AND DIETARY-SODIUM AND DIETARY-SODIUM AND POTASSIUM - A POPULATION STUDY
THE ASSOCIATION BETWEEN BLOOD-PRESSURE, AGE, AND DIETARY-SODIUM AND DIETARY-SODIUM AND POTASSIUM - A POPULATION STUDY
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DOI：
10.1161/01.cir.77.1.53
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发表时间：
1988-01-01
期刊：
影响因子：
37.8
通讯作者：
BARRETTCONNOR, E
中科院分区：
文献类型：
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作者：
KHAW, KT;BARRETTCONNOR, E
我们在南加州30 - 79岁的584名男性和718名女性中，通过24小时饮食回忆，研究了血压与饮食钠和钾摄入量之间的关系。在男性中，年龄调整后的收缩压和舒张压与膳食钠摄入量显著相关，而女性则不然。在男性和女性中，年龄调整后的舒张压与膳食钾摄入量显著负相关。在每种性别中，经校正的收缩压和舒张压与膳食钠/钾比率显著相关;比率的相关性优于单独的钠或钾。这种关系在整个血压和饮食摄入范围内都很明显。男性中存在明显的年龄梯度，血压与钠/钾比值的回归斜率随年龄增加而增加，表明随着年龄的增长，对膳食钠/钾比值的敏感性增加。调整其他饮食变量的摄入量，包括卡路里，蛋白质，碳水化合物，饱和脂肪，酒精，钙和纤维，并没有改变这种关系;调整体重指数降低了女性的关联强度，但在男性中没有。这些结果支持了膳食钠和钾与人群血压相关的假设。
We examined the relationship between blood pressure and dietary sodium and potassium intake estimated from 24 hr diet recall in a population of 584 men and 718 women 30 to 79 years old in Southern California. In men, but not women, age-adjusted systolic and diastolic blood pressure correlated significantly with dietary sodium intake. In both men and women, age-adjusted diastolic blood pressure significantly inversely correlated with dietary potassium intake. Age-adjusted systolic and diastolic blood pressure correlated significantly with the dietary sodium/potassium ratio in each sex; correlations were better for the ratio than for either sodium or potassium alone. The relationship was apparent over the whole range of blood pressure and dietary intake. A marked age gradient was apparent in men, the regression slope for blood pressure vs sodium/potassium ratio increasing with increasing age, suggesting increasing sensitivity to dietary sodium/potassium ratio with age. Adjusting for intake of other dietary variables, including calories, protein, carbohydrate, saturated fat, alcohol, calcium, and fiber, did not alter the relationships; adjusting for body mass index reduced the strength of the association in women but not in men. These results support the hypothesis that dietary sodium and potassium are related to blood pressure within a population.