Regional thigh tissue oxygen saturation during cardiopulmonary bypass predicts acute kidney injury after cardiac surgery
Regional thigh tissue oxygen saturation during cardiopulmonary bypass predicts acute kidney injury after cardiac surgery
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DOI：
10.1007/s10047-020-01175-y
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发表时间：
2020-05-24
影响因子：
1.3
通讯作者：
Miyaji, Kagami
中科院分区：
文献类型：
--
作者：
Sakaki, Kenjiro;Kitamura, Tadashi;Miyaji, Kagami
体外循环术后可出现急性肾损伤，但预测因素尚不清楚。我们研究了局部组织氧饱和度作为体外循环相关急性肾损伤预测指标的可能性。我们分析了2015年1月至2017年3月期间150名非透析成人患者的临床数据，他们接受了择期心脏外科手术。采用近红外光谱分析技术测量局部血氧饱和度。传感器被放置在患者的额头、腹部和大腿上。急性肾损伤发生率：术毕2%，术后24小时13%，术后48小时9%，术后24小时最高。多因素回归分析显示，体外循环期间大腿局部血氧饱和度、氧输送指数、术中和体外循环结束时中性粒细胞计数是急性肾损伤的独立危险因素。受试者-操作特征曲线分析表明，大腿局部血氧饱和度的分界值
Cardiopulmonary bypass-associated acute kidney injury may appear postoperatively, but predictive factors are unclear. We investigated the potential of regional tissue oxygen saturation as a predictor of cardiopulmonary bypass-associated acute kidney injury. We analyzed the clinical data of 150 adult patients not on dialysis who underwent elective cardiac surgical procedures during January 2015-March 2017. Near-infrared spectroscopy was used to measure regional oxygen saturation. Sensors were placed on the patients' forehead, abdomen, and thigh. The incidence of acute kidney injury was 2% at the end of surgery, 13% at 24 h, and 9% at 48 h, with the highest at 24 h after surgery. The multiple regression analysis revealed that the thigh regional oximetry during cardiopulmonary bypass, oxygen delivery index, and neutrophil count at the end of cardiopulmonary bypass and surgery were independent risk factors for acute kidney injury. The receiver-operating characteristic curve analysis suggested that a cutoff of regional oxygen saturation at the thigh of