Epigenetics for ecotoxicologists.
Epigenetics for ecotoxicologists.
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DOI：
10.1002/etc.1707
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发表时间：
2012-02-01
影响因子：
4.1
通讯作者：
Basu, Niladri
中科院分区：
文献类型：
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作者：
Head, Jessica A;Dolinoy, Dana C;Basu, Niladri
越来越多的研究人员认识到表观遗传基因调控在癌症中的作用。阐明表观遗传标记在癌症易感性中的作用已经产生了一个新的焦点，其中治疗目标不仅是基因组，而且是表观基因组一种正在迅速扩展到其他疾病的生物医学方法。表观遗传标记是疾病易感性的生物标志物，是疾病治疗和预防的理想靶点。
Increasingly, researchers are recognizing the role of epigenetic gene regulation in cancer. Elucidating the role of epigenetic marks in susceptibility to cancer has spawned a new focus in which treatment targets not only the genome, but also the epigenome—a biomedical approach that is rapidly expanding to other diseases. Epigenetic marks serve as biomarkers for disease susceptibility, and make ideal targets for disease therapy and prevention.