In Vitro Measurement of Wear in Joint Replacements: A Stratified Approach for Enhanced Reliability “SAFER” Pre-Clinical Simulation Testing
In Vitro Measurement of Wear in Joint Replacements: A Stratified Approach for Enhanced Reliability “SAFER” Pre-Clinical Simulation Testing
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关节置换磨损的体外测量：增强可靠性“SAFER”的分层方法临床前模拟测试
DOI：
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
E. Ingham
中科院分区：
文献类型：
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作者：
J. Fisher;M. Al;S. Williams;L. Jennings;E. Ingham
目前的国际标准要求在标准的步行周期下，使用标准的患者，并使用正确定位的假体进行关节置换术的临床前测试。这些条件不能复制在临床上更广泛的条件下发现的磨损率的广泛变化。本文报道了陶瓷对陶瓷和金属对金属髋关节假体的旋转和平移定位错误对磨损的影响。陶瓷对陶瓷轴承的平动定位错误和微分离导致磨损水平升高，而金属对金属轴承的平动定位错误和旋转定位错误导致磨损水平大幅升高。
Current international standards require pre-clinical testing of joint replacements under a standard walking cycle, with a standard patient, and with correctly positioned prostheses. These conditions do not replicate the wide variation in wear rates found with a wider range of conditions clinically. In this paper the effect of rotational and translational mal-positioning of the components of ceramic-on-ceramic and metal-on-metal hip prostheses on wear is reported. An elevated level of wear was found with translational mal-positioning and microseparation in ceramic-on-ceramic bearings, while a substantially elevated level of wear was found with both translational and rotational mal-positioning in metal-on-metal bearings.