Genomics and Genome Evolution of Mycobacterium tuberculosis
Genomics and Genome Evolution of Mycobacterium tuberculosis
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结核分枝杆菌的基因组学和基因组进化
DOI：
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发表时间：
2012
影响因子：
0.3
通讯作者：
Yao Yu-Feng
中科院分区：
文献类型：
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作者：
Wan Bao-Shan;Zhang Qiu-Fen;Zhou Ai-Ping;Zhao Guo-Ping;Yao Yu-Feng
旨在进行基因组测序的新理论和科学仪器层出不穷，推动着后基因组时代生物学这一历史巨轮不断前行。随着主要致病传染性微生物的基因组序列被……（你提供的英文内容此处不完整）
The endless emergence of new theories and scientific instruments aiming to genome sequencing boosts the large ship of history advance of biology in the post-genomic era.With the genome sequences of major infectious disease-causing microorganisms being determined one by one,the subsequent annotation of gene function and the reconstruction work about protein functions are being carried out.All the efforts are to get a breakthrough understanding of biological characteristics,diagnostic strategies and treatment methods of pathogenic microorganisms.Mycobacterium tuberculosis has been a serious threat to human health globally.All genetic events occurring in the genome evolution play an important role in all aspects such as M.tuberculosis's biological properties,pathogenicity and drug resistance.This review will summarize the origins and genomic features of M.tuberculosis,and discuss the current progress about its genome evolution.