The hypotrichosis-generating shorn (shn) mutation maps to distal chromosome 7 in the Norway rat.
The hypotrichosis-generating shorn (shn) mutation maps to distal chromosome 7 in the Norway rat.
复制标题
挪威大鼠中，导致少毛症的短 (shn) 突变定位于 7 号染色体远端。
DOI：
10.1093/jhered/91.4.345
复制
发表时间：
2000
期刊：
影响因子：
--
通讯作者：
King,TR
中科院分区：
文献类型：
--
作者：
Hall,EH;Lathrop,JA;Medina,B;Mutcherson2nd,RJ;King,TR
We have recently identified an autosomal recessive mutation in the Norway rat that generates an almost complete absence of normal hair. Here we describe a multilocus backcross analysis that was used to map this mutation, named shorn (gene symbolshn), to the distal end of rat chromosome 7. Although this region in rat carries no previously mapped similar mutations, the homologous genomic regions in mouse and human contain several potential homologues and candidate genes.
