Stevens-Johnson syndrome and toxic epidermal necrolysis induced by amifostine during head and neck radiotherapy
Stevens-Johnson syndrome and toxic epidermal necrolysis induced by amifostine during head and neck radiotherapy
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DOI：
10.1016/j.radonc.2008.01.021
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发表时间：
2008-05-01
影响因子：
5.7
通讯作者：
Mockenhaupt, Maja
中科院分区：
文献类型：
--
作者：
Valeyrie-Allanore, Laurence;Poulalhon, Nicolas;Mockenhaupt, Maja
Amifostine is an organic thiophosphate prodrug used for cytoprotection against toxic effects of radiotherapy and chemotherapy. In a European prospective study of SJS/TEN, six patients were suspected to have SJS/TEN associated with amifostine. Our findings suggest that the risk of life-threatening cutaneous adverse reactions to amifostine could be significantly increased. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
