Reliability and validity of a transdiagnostic measure of reward valuation effort.
Reliability and validity of a transdiagnostic measure of reward valuation effort.
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DOI：
10.1037/pas0001107
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发表时间：
2022-05
影响因子：
3.6
通讯作者：
Duffy, Mary E
中科院分区：
文献类型：
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作者：
Keel, Pamela K;Kennedy, Grace A;Rogers, Megan L;Joyner, Keanan J;Bodell, Lindsay P;Forney, K Jean;Duffy, Mary E
为了识别过度奖励消费背后的生物行为机制，奖励评价-努力（RV-E）评估应该：1）在基础科学中进行平行测量，以允许从临床前研究转化为临床研究; 2）从健康到疾病状态的维度量化结构; 3）保持不同诊断类别的相关性。为了解决这些目标，我们开发了一个渐进的比例（PR）的任务，其中RV-E被测量为断点时，参与者的工作访问玩游戏。我们评估了重测信度的断点和收敛和判别效度的解释，这个分数对一个既定的PR任务的食品。在研究1中，女大学生（N=71; 33%的少数民族; 28%的少数民族）完成了游戏和食物的任务，在禁食和进食状态。在研究2中，将患有进食障碍的女性（N=189; 29%为少数民族; 27%为少数民族）（n=158）与对照组（n=31）进行任务比较。游戏任务断点在2周内表现出良好的重测信度（ICC=.91，95%CI [.80-.96]）和禁食任务的收敛效度（r = .51，p< .001）。与动物模型一致，在任务中，与禁食状态相比，进食状态下的断点较低（B（SE）=321.01（552.40），p < .001）。最后，游戏任务证明了判别效度从测量的满足。在研究2中，与对照组相比，饮食失调的女性在两项任务上都表现出更高的断点，并且游戏PR任务断点从禁食状态下降到进食状态。游戏PR任务提供了一种新的方法，用于将RV-E动物模型的结果转化为非临床和临床样本中的可检验假设。
To identify biobehavioral mechanisms underlying excessive reward consumption, reward valuation – effort (RV-E) assessments should 1) parallel measures in basic science to permit translation from preclinical to clinical studies; 2) quantify constructs dimensionally from healthy to disease states; and 3) hold relevance across different diagnostic categories. To address these aims, we developed a progressive ratio (PR) task whereby RV-E is measured as breakpoint when participants worked for access to playing a game. We evaluated test-retest reliability of breakpoint and convergent and discriminant validity of interpretations of this score against an established PR task for food. In Study 1, female undergraduates (N=71; 33% racial minority; 28% ethnic minority) completed the game and food tasks in fasted and fed states. In Study 2, women (N=189; 29% racial minority; 27% ethnic minority) with eating disorders (n=158) were compared to controls (n=31) on tasks. Game task breakpoint demonstrated excellent test-retest reliability (ICC=.91, 95% CI [.80-.96]) over 2 weeks and convergent validity with the fasted food task (r = .51, p< .001). Consistent with animal models, breakpoint was lower in fed compared to fasted states across tasks (B (SE)=321.01 (552.40), p < .001). Finally, the game task demonstrated discriminant validity from measurement of satiation. In Study 2, women with eating disorders demonstrated higher breakpoint on both tasks compared to controls, and game PR task breakpoint decreased from a fasted to fed state. The game PR task offers a novel approach for translating results from animal models of RV-E into testable hypotheses in nonclinical and clinical samples.