Is Location Associated With High Risk of Hypertension? Shimane COHRE Study
Is Location Associated With High Risk of Hypertension? Shimane COHRE Study
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DOI：
10.1038/ajh.2012.36
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发表时间：
2012-07-01
影响因子：
3.2
通讯作者：
Shiwaku, Kuninori
中科院分区：
文献类型：
--
作者：
Hamano, Tsuyoshi;Kimura, Yoshinari;Shiwaku, Kuninori
越来越多的证据表明居住环境与高血压有关。最近，人们的兴趣也转向研究偏远对高血压的可能影响。本研究的目的是探讨偏远的影响，受试者的位置和人口中心之间的最短路径，在农村地区的高血压患病率在Japanes.METHODSWe分析的数据从岛根COHRE研究进行了2006年至2009年在日本农村山区。在排除缺失数据后，我们对1，348人的数据进行了逻辑回归分析。在网络分析中使用了地理信息系统。网络分析确定了受试者所在地与道路网上人口中心之间的距离，并将距离分为三分位数：0- 26，685.8 m =近距离，26，685.9 m-38，350.6 m =中等距离，38，350.7 m-68，070.1 m =远距离。调整潜在混杂因素后，中、远距离高血压（服用降压药或正在接受高血压治疗但未服药）的优势比分别为1.44（95%可信区间（CI）：1.04-1.99）和1.78（95% CI：1.29-2.46）。在考虑测量血压（BP）来定义高血压（服用抗高血压药物或接受高血压治疗而不服药或收缩压（SBP）/舒张压（DBP）>= 140/90 mm Hg）后，优势比不再保持显著性。
BACKGROUNDThere is growing evidence that residential environment is associated with hypertension. Recently, interest has also turned toward examining the possible influence of remoteness on hypertension. The aim of this study is to explore the effect of remoteness, the shortest path between the subject location and the population center, on hypertension prevalence in a rural region in Japan.METHODSWe analyzed data from the Shimane COHRE Study conducted from 2006 to 2009 in rural mountainous regions of Japan. After excluding the missing data, we conducted a logistic regression analysis of the data for 1,348 individuals. Geographic information systems (GIS) were used in the network analysis. Network analysis determined the distance between subject's location and population center on road networks, and the distance was divided into tertiles: 0-26,685.8 m = close distance, 26,685.9 m-38,350.6 m = moderate distance, 38,350.7 m-68,070.1 m = far distance.RESULTSAccording to self-reported hypertension, the odds ratios for hypertension (taking antihypertensive medication or under treatment for hypertension without medication) were 1.44(95% confidence interval (CI): 1.04-1.99) and 1.78(95% CI: 1.29-2.46) in moderate and far distances, respectively, after adjustment for potential confounders. The odds ratios no longer remained significant after considering the measurement of blood pressure (BP) to define hypertension (taking antihypertensive medication or under treatment for hypertension without medication or BP >= 140/90 mm Hg for systolic BP (SBP)/diastolic BP (DBP)).CONCLUSIONSOur findings show that residential remoteness might be associated with a higher risk of hypertension in a rural region in Japan.