Physical activity level and quality of life in long term lung cancer survivors
Physical activity level and quality of life in long term lung cancer survivors
复制标题
DOI：
10.1016/j.lungcan.2012.05.096
复制
发表时间：
2012-09-01
期刊：
影响因子：
5.3
通讯作者：
Clark, Matthew M.
中科院分区：
文献类型：
--
作者：
Nes, Lise Solberg;Liu, Heshan;Clark, Matthew M.
目的：肺癌患者的生活质量(QOL)明显低于其他癌症患者。方法：本研究旨在研究长期肺癌患者(N=1937)的体力活动水平与生活质量的关系。确诊时的平均年龄为65岁，92%是高加索人，51%是男性。调查在肺癌确诊时完成，然后在确诊后平均4.2年。结果：大多数幸存者报告在这两个时间点都有久坐的生活方式。然而，256名幸存者报告说，从诊断到随访，体力活动水平发生了变化。体力活动减少(n=140)与总体、精神、身体、情绪、社交和精神生活质量下降(均为PS<；.001)和症状控制降低有关，如报告的疼痛、干咳、咳嗽伴痰、呼吸急促和疲劳程度(均为PS<；0.05)。相反，增加体力活动(n=116)与改善生活质量(所有PS<；.05)以及改善症状控制(如疼痛频率和严重程度(p<；.01)有关。对于所有参与者来说，那些经常从事体力活动(每天30分钟或更多，每周至少5天)的人报告的生活质量得分显著高于久坐不动的幸存者，并且症状控制更好。结论：结果表明，对于长期肺癌幸存者来说，体力活动与生活质量的变化和症状控制之间存在显著关联，进一步有必要进行研究，探索旨在提高肺癌幸存者活动水平的干预措施。(C)2012爱思唯尔爱尔兰有限公司。保留所有权利。
Purpose: Lung cancer is associated with a multitude of challenges, and lung cancer survivors report significantly lower quality of life (QOL) than other cancer survivors.Methods: This study aimed to examine the relationship between physical activity level and QOL in a large sample of long term lung cancer survivors (N = 1937). Average age at diagnosis was 65 years, 92% were Caucasian, and 51% male. Surveys were completed at lung cancer diagnosis and then average 4.2 years post-diagnosis.Results: Most survivors reported having a sedentary lifestyle at both timepoints. However, 256 survivors reported a change in physical activity level from diagnosis to follow-up. Decreased physical activity (n = 140) was associated with decreased overall, mental, physical, emotional, social, and spiritual QOL (all ps < .001) and decreased symptom control as seen in reported pain, dry coughing, coughing with phlegm, shortness of breath, and level of fatigue (all ps < .05). In contrast, increased physical activity (n = 116) was associated with improved QOL (all ps < .05), and improved symptom control as seen in frequency and severity of pain (p < .01). For all participants, those engaging in regular physical activity (30 min or more per day, at least five days per week) reported significantly higher QOL scores (all ps < .001), and better symptom control than more sedentary survivors.Conclusions: Results indicate a significant association between change in physical activity and QOL and symptom control for long term lung cancer survivors, and research exploring interventions designed to improve activity level for lung cancer survivors is further warranted. (c) 2012 Elsevier Ireland Ltd. All rights reserved.