Lateral cerebral ventricular enlargement in chronic schizophrenia.
Lateral cerebral ventricular enlargement in chronic schizophrenia.
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慢性精神分裂症的侧脑室扩大。
DOI：
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发表时间：
1979
影响因子：
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通讯作者：
Richard Jed Wyatt
中科院分区：
文献类型：
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作者：
D. R. Weinberger;E. Torrey;Andreas Neophytides;Andreas Neophytides;Richard Jed Wyatt
为了研究脑室增大是否与慢性精神分裂症有关，对73名精神病患者的计算机断层扫描结果与56名年龄小于50岁的无症状志愿者进行了比较。58名慢性精神分裂症患者的心室大小明显大于对照组。在慢性精神分裂症患者中，40%在控制范围之外；53%超过对照平均值的2个标准差。疾病持续时间和住院时间与心室大小无关。44例从未接受过电击治疗的慢性精神分裂症患者的心室比对照组大。一组7名非慢性精神分裂症患者也有心室增大；8名患有精神分裂或非精神分裂的患者与对照组没有差异。本研究表明，侧脑室增大与慢性精神分裂症有关；这表明这不是治疗的结果。
To investigate if cerebral ventricular enlargement is associated with chronic schizophrenia, computerized tomography scans from 73 psychiatric patients were compared with 56 asymptomatic volunteers all less than 50 years old. Ventricular size was significantly greater in the subgroup of 58 chronic schizophrenic patients than in the controls. Of the chronic schizophrenic patients, 40% were outside the control range; 53% exceeded 2 SDs of the control mean. Neither duration of illness nor length of hospitalization correlated with ventricular size. The 44 chronic schizophrenic patients who had never been treated with electroshock therapy (EST) had larger ventricles than controls. A group of seven nonchronic schizophrenic patients also had enlarged ventricles; the eight patients who were either schizoaffective or nonschizophrenic did not differ from controls. This study shows that lateral cerebral ventricular enlargement is associated with chronic schizophrenia; it suggests that this is not a result of treatment.