A Prospective, Randomised EORTC Intergroup Phase 3 Study Comparing the Oncologic Outcome of Elective Nephron-Sparing Surgery and Radical Nephrectomy for Low-Stage Renal Cell Carcinoma
A Prospective, Randomised EORTC Intergroup Phase 3 Study Comparing the Oncologic Outcome of Elective Nephron-Sparing Surgery and Radical Nephrectomy for Low-Stage Renal Cell Carcinoma
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DOI：
10.1016/j.eururo.2010.12.013
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发表时间：
2011-04-01
期刊：
影响因子：
23.4
通讯作者：
Sylvester, Richard
中科院分区：
文献类型：
--
作者：
Van Poppel, Hendrik;Da Pozzo, Luigi;Sylvester, Richard
背景：保留肾元手术（NSS）可以安全地进行，并发症发生率略高于根治性肾切除术（RN），但缺乏肿瘤有效性的证据。目的：比较总生存期（OS）和进展时间。设计、环境和参与者：从1992年3月到2003年1月，541例小(
Background: Nephron-sparing surgery (NSS) can safely be performed with slightly higher complication rates than radical nephrectomy (RN), but proof of oncologic effectiveness is lacking.Objective: To compare overall survival (OS) and time to progression.Design, setting, and participants: From March 1992 to January 2003, when the study was prematurely closed because of poor accrual, 541 patients with small (