Vitamin A status among children in China
Vitamin A status among children in China
复制标题
DOI：
10.1017/phn2006944
复制
发表时间：
2006-12-01
影响因子：
3.2
通讯作者：
Lin Liangming
中科院分区：
文献类型：
--
作者：
Jiang Jingxiong;Toschke, Andre Michael;Lin Liangming
目的：本研究的目的是评估中国6岁以下儿童维生素A缺乏症（VAD）的患病率，并确定VAD的危险人群。设计：在中国沿海、内陆和西部地区的14个省份进行横断面调查。设置：在每个省随机选取1个市（市区）和2个县（农村）作为调查区域。对象：每个调查区随机抽取0-6岁儿童200名左右。从每个孩子身上采集了血液样本。通过对母亲或主要照顾者的访谈获得社会人口统计学和营养方面的数据。荧光微量分析测定血清视黄醇浓度。结果：7826例0-6岁儿童中957例（12.2%）出现VAD（血清视黄醇< 0.7 μ mol l(-1)）， 39例（0.5%）出现严重VAD（血清视黄醇< 0.35 μ mol l(-1)）。少数民族母亲（22.7%）、教育程度较低母亲（19.8%）和西部贫困地区（17.4%）的儿童在1 ~ 10岁时VAD患病率最高。结论：VAD是中国儿童的一个营养问题。生活在西部贫困地区、母亲为少数民族或母亲受教育程度较低的儿童患VAD的风险较高。
Objective: The objective of this study was to assess the prevalence of vitamin A deficiency (VAD) in children under 6 years old in China and to identify risk groups for VAD.Design: A cross-sectional survey was conducted in 14 provinces from coastal, inland and western geographic areas in China.Setting: One city (urban) and two counties (rural) were randomly selected from each province as survey areas.Subjects: About 200 children aged 0-6 years were randomly selected in each survey area. A blood sample was collected from each child. Data on sociodemographics and nutrition were obtained by interview of the mother or principal caregiver. Fluorescence microanalysis was used to analyse serum retinol concentration.Results: VAD (serum retinol < 0.7 mu mol l(-1)) was observed in 957 out of 7826 children aged 0-6 years (12.2% of the entire study population), whereas severe VAD (serum retinol < 0.35 mu mol l(-1)) was found in 39 children (0.5%). The highest prevalences of VAD at > 1 year of age were observed among children of mothers with minority ethnicity (22.7%) or poor education (19.8%) and in the poor western area (17.4%).Conclusions: VAD is a nutritional problem in children in China. Children living in the poor western area, having a mother with minority ethnicity or a mother with poor education have a high risk of VAD.