Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors.
Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors.
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DOI：
10.1039/c1nr11149c
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发表时间：
2012-01
期刊：
影响因子：
6.7
通讯作者：
Z. Yin;Qiyuan He;Xiao Huang;Juan Zhang;Shixin Wu;Peng Chen;Gang Lu;Qichun Zhang;Q. Yan
中科院分区：
文献类型：
--
作者：
Z. Yin;Qiyuan He;Xiao Huang;Juan Zhang;Shixin Wu;Peng Chen;Gang Lu;Qichun Zhang;Q. Yan
采用Langmuir-Blodgett （LB）法在Si/SiO(2)晶圆上制备了大面积、连续、少层还原氧化石墨烯（rGO）薄膜。在还原氧化石墨烯上光化学还原Pt纳米粒子（PtNPs）后，得到的PtNPs/rGO复合材料作为导电通道在溶液门控场效应晶体管（FET）中，用于高灵敏度（2.4 nM）实时检测单链DNA （ssDNA）的杂交。这种简单而有效的制造rgo基晶体管的方法显示了大规模生产石墨烯基电子生物传感器的巨大潜力。
A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO(2) wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.