Exercise immunology: Practical applications

Exercise immunology: Practical applications
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DOI:
10.1055/s-2007-972705
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发表时间:
1997-03-01
影响因子:
2.5
通讯作者:
Nieman, DC
Nieman, DC
中科院分区:
医学4区
文献类型:
--
作者:
Nieman, DC

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在过去的95年里,专门研究运动和免疫学的论文有629篇(其中60%是在20世纪90年代发表的)。在公众健康和运动努力方面具有实际重要性的主要发现包括:(a)在对急性运动(运动免疫学最常研究的领域)的反应中,外周淋巴组织和循环之间发生了免疫细胞的快速交换。这种反应取决于许多因素,包括运动的强度、持续时间和模式、激素和细胞因子的浓度、体温的变化、血流量、水合状态和体位。在所有免疫细胞中,自然杀伤细胞(NIK)、中性粒细胞和巨噬细胞(先天免疫系统)似乎对急性运动的影响最敏感,无论是在数量上还是在功能上。一般来说,持续时间适中的急性运动发作(
During the last 95 years, 629 papers (60% in the 1990s) dealing specifically with exercise and immunology have been published. Major findings of practical importance interms of public hearth and athletic endeavor include: (a) In response to acute exercise (the most frequently studied area of exercise immunology), a rapid interchange of immune cells between peripheral lymphoid tissues and the circulation occurs. The response depends on many factors, including the intensity, duration, and mode of exercise, concentrations of hormones and cytokines, change in body temperature, blood flow, hydration status, and body position. Of all immune cells, natural killer (NIK) cells, neutrophils, and macrophages (of the innate immune system) appear to be most responsive to the effects of acute exercise, both in terms of numbers and function. In general, acute exercise bouts of moderate duration (