Quantitative Psychomotor Dysfunction in Schizophrenia: A Loss of Drive, Impaired Movement Execution or Both?
Quantitative Psychomotor Dysfunction in Schizophrenia: A Loss of Drive, Impaired Movement Execution or Both?
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DOI：
10.1159/000355293
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发表时间：
2013-01-01
影响因子：
3.2
通讯作者：
Morrens, Manuel
中科院分区：
文献类型：
--
作者：
Docx, Lise;Sabbe, Bernard;Morrens, Manuel
目的：本研究的目的是探讨定性精神运动表现水平和阴性综合征亚方面对精神分裂症患者定量运动活动水平的预测价值。方法：纳入27例稳定的精神分裂症患者和22例年龄和性别匹配的健康对照。对所有参与者进行了广泛的精神运动表现测试（手指叩击测试、普渡钉板测试、线条复制测试、神经评估量表、萨尔皮特里埃发育迟缓评定量表）、临床评定量表（阳性和阴性综合征量表）和24小时活动记录仪。结果：相关分析显示，运动活动水平与进化以及临床评估的精神运动减缓有关。然而，在回归模型中，只有进化被发现是精神分裂症患者运动活动水平的重要预测因子；精神运动表现测试和情绪表达缺陷的严重程度都与模型无关。结论：定性和定量精神运动缺陷在稳定的精神分裂症患者中似乎是独立的现象。精神分裂症患者运动活动的减少与动力的丧失有关，而与运动执行质量的问题无关。(C) 2013 S. Karger AG，巴塞尔
Aims: The aim of the present study was to investigate the predictive value of qualitative psychomotor performance levels and subaspects of the negative syndrome for quantitative motor activity levels in patients with schizophrenia. Methods: Twenty-seven stabilized patients with schizophrenia and 22 age- and sex-matched healthy controls were included in the study. An extensive battery of psychomotor performance tests (Finger Tapping Test, Purdue Pegboard Test, Line Copying Test, Neurological Evaluation Scale, Salpetriere Retardation Rating Scale), clinical rating scales (Positive and Negative Syndrome Scale) and 24-hour actigraphy were administered to all participants. Results: Correlational analyses showed that motor activity levels were associated with avolition as well as clinically assessed psychomotor slowing. However, in a regression model, only avolition was found to be a significant predictor for motor activity levels in patients with schizophrenia; none of the psychomotor performance tests nor the severity of emotional expressivity deficits contributed to the model. Conclusion: Qualitative and quantitative psychomotor deficits seem to be independent phenomena in stabilized patients with schizophrenia. The diminishing in motor activity in patients with schizophrenia is related to a loss of drive and not to problems in the quality of movement execution. (C) 2013 S. Karger AG, Basel