CIRCULATING INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR IN SEPTIC SHOCK AND EXPERIMENTAL ENDOTOXIN FEVER
CIRCULATING INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR IN SEPTIC SHOCK AND EXPERIMENTAL ENDOTOXIN FEVER
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DOI:
10.1093/infdis/161.1.79
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发表时间:
1990-01-01
影响因子:
6.4
通讯作者:
DINARELLO, CA
中科院分区:
文献类型:
--
作者:
CANNON, JG;TOMPKINS, RG;DINARELLO, CA
Interleukins (IL)-1.beta. and -1.alpha. and tumor necrosis factor (TNF-.alpha.) were measured by radioimmunoassay in plasma samples from 44 healthy individuals, 15 patients in septic shock, and 6 volunteers infused with endotoxin. Plasma IL-1.alpha. levels were low (40 pg/ml) or undetectable in all situation. In 67% of the healthy subjects, plasma IL-1.beta. levels were