The Different Magnetic Resonance Communities Join Forces for Progress in DNP: an Editorial for the Special Issue on DNP

The Different Magnetic Resonance Communities Join Forces for Progress in DNP: an Editorial for the Special Issue on DNP
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不同的磁共振界携手推动 DNP 的进步:DNP 特刊的社论

DOI:
10.1007/s00723-012-0368-z
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发表时间:
2012
影响因子:
1
通讯作者:
W. Köckenberger
W. Köckenberger
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
A. V. Atsarkin;W. Köckenberger

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This special issue of Applied Magnetic Resonance is the result of an attempt to show the very broad range of current research activities revolving around the central theme of dynamic nuclear polarization (DNP) and the impact DNP is currently making in many different scientific disciplines. It is fascinating to see how an idea that is almost as old as the whole field of nuclear magnetic resonance (NMR) is now revolutionizing the way people think about the maximal sensitivity that can be achieved in NMR experiments. Nowadays, scientists try to produce fully polarized nuclear spin systems for use as highly sensitive probes in medical diagnostic imaging or to generate high spin polarization on surfaces to investigate conformation of molecules in the boundary layers. In particular, two developments have tremendously stimulated the recent progress in DNP research. First, through the continuous and persistent efforts of Prof. R Griffin at the Massachusetts Institute of Technology, Boston US, robust hardware and experimental strategies are now available for solid-state magic angle spinning NMR experiments in conjunction with DNP. The second development was the use of low-temperature DNP followed by a fast rise in temperature to produce solutions containing highly polarized spin systems. This technique is now commonly referred to as dissolution DNP and has been conceived and developed by Prof. K Golman and Prof. J.-H. Ardenkjaer-Larsen in Malmö, Sweden. The impact that these two major achievements are currently generating on the design of novel strategies for NMR spectroscopy and MR imaging and on increasing the range of applications cannot be rated highly enough. On the other hand, it is clear that the idea of using the electrons to generate