Complications Encountered in the Treatment of Benign Thyroid Nodules with US-guided Radiofrequency Ablation: A Multicenter Study

Complications Encountered in the Treatment of Benign Thyroid Nodules with US-guided Radiofrequency Ablation: A Multicenter Study
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DOI:
10.1148/radiol.11110416
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发表时间:
2012-01-01
期刊:
影响因子:
19.7
通讯作者:
Na, Dong Gyu
Na, Dong Gyu
中科院分区:
医学1区
文献类型:
--
作者:
Baek, Jung Hwan;Lee, Jeong Hyun;Na, Dong Gyu

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目的:评估射频(RF)消融治疗良性甲状腺结节并发症的临床表现和影像学特征。材料和方法:这项回顾性研究获得了机构审查委员会的批准,并放弃了知情同意。从2002年6月到2009年9月,13个甲状腺中心(韩国甲状腺放射学会会员)的1459名患者使用带有内部冷却电极的射频系统对1543个甲状腺结节进行了射频消融。对主要和次要并发症的数量和类型进行了评估。结果:作者观察到 48 种并发症 (3.3%),其中 20 种主要并发症,28 种轻微并发症。主要并发症是声音变化(n = 15)、臂丛神经损伤(n = 1)、肿瘤破裂(n = 3)和永久性甲状腺功能减退症(n = 1)。轻微并发症为血肿(n = 15)、皮肤烧伤(n = 4)和呕吐(n = 9)。除1例永久性甲状腺功能减退症和1例手术治疗外,其余患者均自然康复。结论:射频消融虽然并发症发生率较低,但可能会出现多种并发症,因此,射频消融治疗的并发症发生率较低。了解并发症和建议的技术技巧可以预防并发症或正确处理发生的并发症。 (C) 北美放射学会,2011
Purpose: To evaluate clinical aspects and imaging features of complications encountered in the treatment of benign thyroid nodules with radiofrequency (RF) ablation.Materials and Methods: Institutional review board approval was obtained for this retrospective study, and informed consent was waived. From June 2002 to September 2009, 1459 patients underwent RF ablation of 1543 thyroid nodules with an RF system with internally cooled electrodes at 13 thyroid centers, which were members of Korean Society of Thyroid Radiology. Numbers and types of major and minor complications were assessed.Results: The authors observed 48 complications (3.3%), 20 major and 28 minor. The major complications were voice changes (n = 15), brachial plexus injury (n = 1), tumor rupture (n = 3), and permanent hypothyroidism (n = 1). The minor complications were hematoma (n = 15), skin burn (n = 4), and vomiting (n = 9). All patients recovered spontaneously except for one with permanent hypothyroidism and one who underwent surgery.Conclusion: Although the complication rate of RF ablation is low, various complications may occur; comprehension of complications and suggested technical tips may prevent complications or properly manage those that occur. (C) RSNA, 2011