Heart rate variability in insomniacs and matched normal sleepers
Heart rate variability in insomniacs and matched normal sleepers
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DOI：
10.1097/00006842-199809000-00017
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发表时间：
1998-09-01
影响因子：
3.3
通讯作者：
Arand, DL
中科院分区：
文献类型：
--
作者：
Bonnet, MH;Arand, DL
目的：假设心理生理失眠症的心率升高，体温和全身代谢率升高，在其心脏周期数据的光谱分析中，低频和高频功率也会增加。方法：在36小时的睡眠实验室住院期间，对12个客观定义的失眠症和年龄，性别和体重匹配的对照组进行了正常睡眠评估。结果：与对照组相比，在失眠症的所有睡眠阶段，心脏周期降低（即心率增加），并且其SD在失眠的所有阶段都降低。光谱分析显示，与在所有睡眠的所有阶段相比，失眠症的低频功率显着增加和高频功率降低。结论：由于低频频谱功率增加是交感神经系统活动增加的指标，因此这些数据表明，慢性失眠症可能会增加与交感神经系统活动增加有关的疾病（例如冠状动脉疾病）的风险。
Objective: It was hypothesized that psychophysiological insomniacs, who have been shown to have elevated heart rate, body temperature, and whole body metabolic rate, would also have increased low frequency and decreased high frequency power in the spectral analysis of their heart period data. Method: Groups of 12 objectively defined insomniacs and age-, sex-, and weight-matched controls with normal sleep were evaluated on sleep and EKG measures over a 36-hour sleep laboratory stay. Results: Heart period was decreased (ie, heart rate was increased) and its SD was decreased in all stages of sleep in the insomniacs compared with the controls. Spectral analysis revealed significantly increased low frequency power and decreased high frequency power in insomniacs compared with controls across all stages of sleep. Conclusions: Because increased low frequency spectral power is an indicator of increased sympathetic nervous system activity, these data imply that chronic insomniacs could be at increased risk for the development of disorders, such as coronary artery disease, that are related to increased sympathetic nervous system activity.