Thermal injury and gastrointestinal function. I. Small intestinal nutrient absorption and DNA synthesis.
Thermal injury and gastrointestinal function. I. Small intestinal nutrient absorption and DNA synthesis.
复制标题
热损伤与胃肠功能。
DOI：
10.1097/00004630-198611000-00004
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Walker,WA
中科院分区：
文献类型：
--
作者：
Carter,EA;Udall,JN;Kirkham,SE;Walker,WA
研究了热水烫伤对大鼠小肠营养吸收和DNA合成的影响。烧伤大鼠表现出小肠粘膜重量下降和营养物质（钙、葡萄糖或氨基酸）小肠运输改变。此外，急性烧伤后18小时，3h -胸腺嘧啶在体内肠DNA内掺入减少，体外肠胸腺嘧啶激酶活性降低。这些数据表明，急性烧伤创伤产生严重应激后，小肠营养吸收和DNA合成发生改变。这些改变可能会影响肠道向烧伤患者输送营养物质。
The effect of acute burn trauma, produced by scalding hot water, on rat small intestinal nutrient absorption and DNA synthesis has been examined. Burned rats showed decresed small-intestine mucosal weight and altered small-intestine transport of nutrients (calcium, glucose, or amino acid) in vitro. In addition, there was decreased3H-thymidine incorporation into intestinal DNA in vivo and decreased intestinal thymidine kinase activity in vitro 18 hours after acute burn. These data suggest that after the severe stress produced by acute burn trauma, there is altered small-intestine nutrient absorption and DNA synthesis. These alterations may affect delivery of nutrients by the gut to the burn patient.