Isolation and characterization of rat lymphatic endothelial cells.
Isolation and characterization of rat lymphatic endothelial cells.
复制标题
DOI：
--
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
M. Djoneidi;P. Brodt
中科院分区：
文献类型：
--
作者：
M. Djoneidi;P. Brodt
取大鼠胸导管组织块，单层培养淋巴管内皮细胞。细胞呈典型的鹅卵石样形态，表达von Willebrand因子(第VIII因子相关抗原)和血管紧张素转换酶，摄取乙酰化低密度脂蛋白，与血管内皮细胞难以区分。这些细胞的可获得性将有助于利用大鼠实验模型进行淋巴管内皮细胞的功能研究。
Monolayer cultures of rat lymphatic endothelial cell were obtained from explants of rat thoracic ducts. The cells displayed a typical cobblestone morphology, expressed von Willebrand factor (factor VIII-associated antigen) and angiotensin converting enzyme, and took up acetylated-low density lipoprotein, being indistinguishable by these criteria from blood vessel endothelial cells. The availability of these cells will facilitate the use of rat experimental models for functional studies of lymphatic endothelium.