Near-infrared light propagation in an adult head model with refractive index mismatch
Near-infrared light propagation in an adult head model with refractive index mismatch
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DOI：
10.4218/etrij.05.0104.0056
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发表时间：
2005-08-01
期刊：
影响因子：
1.4
通讯作者：
Lee, JH
中科院分区：
文献类型：
--
作者：
Kim, S;Lee, JH
我们使用广泛的蒙特卡罗 (MC) 模拟研究成人头部模型中的近红外光 (NIR) 传播。成人头部模型为四层板，由表层、脑脊液层、灰质层和白质层组成。我们研究了折射率不匹配对模型的影响，计算了脑脊液层各种折射率的检测光强度、平均飞行时间和每层的部分平均飞行时间，作为源探测器间距的函数。蒙特卡罗模拟表明，折射率失配呈现出非常丰富的结果，包括检测到的战斗强度快速衰减以及部分平均飞行时间随源探测器间距的峰值和交叉。我们还研究了不同源-探测器间距下的空间灵敏度分布，讨论了折射率失配对模型的影响。
We investigate near-infrared light (NIR) propagation in a model of an adult head using an extensive Monte Carlo (MC) simulation. The adult head model is a four-layered slab which consists of a surface layer, a cerebrospinal fluid layer, a gray-matter layer, and a white-matter layer. We study the effects of a refractive index mismatch on the model, calculating the intensity of detected light, mean flight time, and partial mean flight time of each layer for various refractive indices of the cerebrospinal fluid layer as functions of source-detector spacing. The Monte Carlo simulation shows that the refractive index mismatch presents very rich results including rapidly decaying intensity of detected fight and a peak and cross-over in the partial mean flight time with source-detector spacing. We also investigate spatial sensitivity profiles at various source-detector spacings, discussing the index mismatch effect on the model.