Effect of holothurin on Trypanosoma musculi infection in three strains of mice.
Effect of holothurin on Trypanosoma musculi infection in three strains of mice.
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海参素对三品系小鼠锥虫感染的影响。
DOI：
10.1111/j.1550-7408.1981.tb02827.x
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Narain,NK
中科院分区：
文献类型：
--
作者：
Sen,DK;Lankaranifard,G;Narain,NK
本文通过观察小鼠体内寄生虫数量的变化，研究了海参素（一种海洋生物毒素）对小鼠抗肌肉锥虫的影响。在锥虫感染之前和同时用海参素处理的Swiss韦伯斯特（SW）、Beige（BG）和Black（BL）小鼠的寄生虫血症低于对照组。在用锥虫感染后治疗的小鼠中观察到更高水平的寄生虫血症。施用海参素的时间似乎是观察到的效果的重要因素。寄生虫血症的微小变化似乎与小鼠品系相关。
The effect of holothurin (a marine biotoxin) on the resistance of mice toTrypanosoma musculiwas measured by studying changes in the parasite population in vivo. Swiss Webster (SW), Beige (BG), and Black (BL) mice treated with holothurin prior to and simultaneously with infection of trypanosomes had lower parasitemias than controls. Higher levels of parasitemia were observed in mice treated after infection with trypanosomes. The timing of administration of holothurin appeared to be an important factor in the observed effect. The minor variations in the parasitemia seemed to be related to the mouse strain.