Blood and marrow transplantation activity in Europe 1996
Blood and marrow transplantation activity in Europe 1996
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1996年欧洲的血液和骨髓移植活动
DOI：
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发表时间：
1998
影响因子：
4.8
通讯作者：
For the Japan Study Group for Cell Therapy and Transplantation
中科院分区：
文献类型：
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作者：
A. Gratwohl;J. Passweg;H. Baldomero;J. Hermans;For the Japan Study Group for Cell Therapy and Transplantation
按适应症、供体类型和干细胞来源报告了1996年欧洲血液和骨髓移植小组成员和有关欧洲小组的移植活动。考虑到前几年的报告，描述了每种适应症的年度移植数量、每个参与国的移植率、按适应症分列的移植率变化以及供体类型和干细胞来源的变化。据报道，1996年欧洲共有来自31个国家的382个小组进行了14593例血液或骨髓移植。其中，4393例（30%）为同种异体移植，10200例（70%）为自体移植。在自体移植中，978例（10%）来自骨髓，9222例（90%）来自外周血干细胞或骨髓和外周血干细胞联合移植。在同种异体移植中，3252例（74%）为骨髓移植，1141例（26%）为外周血干细胞移植。1996年的主要适应症是白血病，有4961例移植（34%），70%为同种异体移植，30%为自体移植;淋巴瘤，有5505例移植（38%），6%为同种异体移植，94%为自体移植;实体瘤，有3484例移植（24%），1%为同种异体移植，99%为自体移植;非恶性疾病，643例移植（4%），92%为同种异体，8%为自体。各国之间存在重大差异。每个国家每1000万居民的移植率从0到>500不等（中位数为每1000万居民202例）。自1990年以来，在多发性骨髓瘤和乳腺癌中观察到自体移植新适应症的最显著增加。这些数据反映了欧洲血液和骨髓移植的最新变化和现状。它们为病人咨询和保健规划提供了基础。
Transplant activity by members of the European Group for Blood and Marrow Transplantation (EBMT) and related European teams is reported for 1996 by indication, donor type and stem cell source. Bearing in mind reports from previous years, the annual numbers of transplants for each indication, transplant rates for each participating country, changes in transplant rates by indication and changes in donor types and stem cell sources are described. A total 14 593 blood or marrow transplants, performed in Europe by 382 teams from 31 countries, were reported in 1996. Of these, 4393 (30%) were allogeneic and 10 200 (70%) were autologous transplants. Of the autologous transplants, 978 (10%) were bone marrow derived, 9222 (90%) from peripheral blood stem cells or combined bone marrow and peripheral blood stem cell transplants. Of the allogeneic transplants, 3252 (74%) were bone marrow and 1141 (26%) were peripheral blood stem cell transplants. Main indications in 1996 were leukemias with 4961 transplants (34%), 70% allogeneic and 30% autologous; lymphomas with 5505 transplants (38%), 6% allogeneic and 94% autologous; solid tumours with 3484 transplants (24%), 1% allogeneic and 99% autologous; non-malignant disorders with 643 transplants (4%), 92% allogeneic and 8% autologous. There are major differences between countries. Transplant rates per 10m inhabitants per country ranged from 0 to >500 (median 202 per 10 m inhabitants). The most pronounced increase since 1990 for new indications in autologous transplants was observed in multiple myeloma and carcinoma of the breast. These data reflect recent changes and present status of blood and marrow transplantation in Europe. They provide a basis for patient counselling and health care planning.
影响因子：
6.2
作者：
Bortin,MM;Rimm,AA
通讯作者：
Rimm,AA