Resistive index of prostate capsular arteries: a newly identified parameter to diagnose and assess bladder outlet obstruction in patients with benign prostatic hyperplasia.
Resistive index of prostate capsular arteries: a newly identified parameter to diagnose and assess bladder outlet obstruction in patients with benign prostatic hyperplasia.
复制标题
前列腺囊动脉阻力指数：一个新确定的参数，用于诊断和评估良性前列腺增生患者膀胱出口梗阻。
DOI：
10.1016/j.juro.2012.04.114
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发表时间：
2012
影响因子：
6.6
通讯作者：
Jianquan Hou
中科院分区：
文献类型：
--
作者：
Xuefeng Zhang;Gang Li;Xue;Xiaodong Mo;Linkun Hu;Yueqin Zha;Jianquan Hou
目的我们评估良性前列腺增生男性前列腺囊动脉阻力指数与膀胱出口梗阻严重程度的关系。材料与方法最终纳入74名经组织学诊断为良性前列腺增生的患者。由泌尿科医师进行尿动力学检查以确定膀胱出口梗阻。良性前列腺增生患者测量的基线参数为前列腺囊动脉阻力指数、国际前列腺症状评分、生活质量评分、总前列腺和移行区体积以及移行区指数。制作ROC曲线，计算ROC AUC，评价前列腺囊动脉阻力指数、国际前列腺症状评分、梗阻症状、前列腺总体积和移行区体积、膀胱出口梗阻移行区指数的诊断性能。结果膀胱出口梗阻患者与无膀胱出口梗阻患者的阻力指数存在显着性差异，阻力指数与梗阻程度的系数最高（r = 0.712，p <0.0001）。以 0.69 为截止值，电阻指数区分有或没有膀胱出口梗阻的患者，敏感性为 78%，特异性为 86.4%。前列腺囊动脉阻力指数最大AUC为0.823。结论良性前列腺增生相关性膀胱出口梗阻患者的前列腺包膜动脉阻力指数显着高于无膀胱出口梗阻患者。阻力指数可能作为诊断和评估良性前列腺增生患者膀胱出口梗阻的新指标。
PurposeWe evaluated the association of the resistive index of the prostate capsular arteries and bladder outlet obstruction severity in men with benign prostatic hyperplasia.Materials and MethodsA total of 74 patients histologically diagnosed with benign prostatic hyperplasia were ultimately enrolled in this prospective study. Urodynamics were performed by a urologist to determine bladder outlet obstruction. Baseline parameters measured in patients with benign prostatic hyperplasia were the prostate capsular artery resistive index, International Prostate Symptom Score, quality of life score, total prostate and transition zone volume, and the transition zone index. ROC curves were produced to calculate the ROC AUC and evaluate the diagnostic performance of the prostate capsular artery resistive index, International Prostate Symptom Score, obstructive symptoms, total prostate and transition zone volume, and the transition zone index for bladder outlet obstruction.ResultsSignificant difference between patients with and without bladder outlet obstruction was observed in the resistive index, which showed the highest coefficient with the degree of obstruction (r = 0.712, p <0.0001). At a cutoff of 0.69 the resistive index distinguished patients with and without bladder outlet obstruction with 78% sensitivity and 86.4% specificity. The prostate capsular artery resistive index had the maximum AUC of 0.823.ConclusionsThe prostate capsular artery resistive index is significantly higher in patients with benign prostatic hyperplasia related bladder outlet obstruction than in those without such obstruction. The resistive index might serve as a novel indicator to diagnose and assess bladder outlet obstruction in patients with benign prostatic hyperplasia.