REBASE--restriction enzymes and DNA methyltransferases.
REBASE--restriction enzymes and DNA methyltransferases.
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DOI：
10.1093/nar/gki029
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Macelis D
中科院分区：
文献类型：
--
作者：
Roberts RJ;Vincze T;Posfai J;Macelis D
REBASE是一个关于限制性内切酶、DNA甲基转移酶和限制性修饰相关蛋白质信息的综合数据库。它包含已发表和未发表的工作与信息的识别和切割位点，异构体，商业可用性，晶体和序列数据。还包括实验表征的归巢核酸内切酶。此外，REBASE还包含有关限制性内切核酸酶甲基化敏感性的完整和最新信息。一个广泛的分析包括限制性修饰系统，预计将存在于测序的细菌和古细菌基因组从GenBank。REBASE的内容可通过网页（http：//rebase.neb.com/rebase/rebase.html）浏览，也可通过FTP（ftp.neb.com）选择汇编，还可通过电子邮件要求每月更新。
REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in restriction–modification. It contains both published and unpublished work with information about recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data. Experimentally characterized homing endonucleases are also included. Additionally, REBASE contains complete and up-to-date information about the methylation sensitivity of restriction endonucleases. An extensive analysis is included of the restriction–modification systems that are predicted to be present in the sequenced bacterial and archaeal genomes from GenBank. The contents of REBASE are available by browsing from the web (http://rebase.neb.com/rebase/rebase.html) and through selected compilations by ftp (ftp.neb.com) and as monthly updates that can be requested via email.