Poly( L -lactic acid) Microfiltration Membrane Formation via Thermally Induced Phase Separation with Drying
Poly( L -lactic acid) Microfiltration Membrane Formation via Thermally Induced Phase Separation with Drying
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DOI：
10.1252/jcej.11we030
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发表时间：
2011-07
影响因子：
0.8
通讯作者：
Takaaki Tanaka;Masato Ueno;Youhei Watanabe;Tomoaki Kouya;M. Taniguchi;D. R. Lloyd
中科院分区：
文献类型：
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作者：
Takaaki Tanaka;Masato Ueno;Youhei Watanabe;Tomoaki Kouya;M. Taniguchi;D. R. Lloyd
以聚L-乳酸（PLLA）-1，4-二氧六环-水溶液为原料，采用热致相分离法制备了PLLA微滤膜。由此产生的膜用于保留细菌细胞和渗透蛋白质分子。由10-12.5%聚合物溶液制备的膜仅保留细胞悬液中20%的细菌细胞。将聚合物浓度从12.5%增加到15%显著地将细菌细胞保留提高到60%。通过将浇铸温度从40 °C升高到50°C，保持率进一步增加到90%。通过在淬灭之前干燥聚合物溶液2分钟，电池保留率达到99%。在60°C或更高的温度下流延并干燥5分钟或更长的时间段使得膜不均匀和/或增加膜电阻。通过在淬灭之前干燥聚合物溶液，改变膜表面附近的多孔结构，使得膜保留细菌细胞。该膜以筛网过滤器的方式保留细菌细胞。在这项研究中开发的膜将是有用的作为预过滤器在生化过程中，以提高最终过滤器的寿命，并减少工业废物，由于是由可堆肥的聚合物。
Microfiltration membranes of poly(L-lactic acid) (PLLA), which is a major biodegradable plastic, were prepared from PLLA–1,4-dioxane–water solutions via the thermally induced phase separation. The resulting membranes are used to retain bacterial cells and permeate protein molecules. Only 20% of the bacterial cells in cell suspensions were retained by the membranes prepared from 10–12.5% polymer solution. Increasing the polymer concentration from 12.5 to 15% markedly elevated the bacterial cell retention to 60%. The retention further increased to 90% by elevating the casting temperature from 40 to 50°C. By drying the polymer solution for 2 min before quenching, the cell retention reached 99%. Casting at temperatures of 60°C or higher and drying for periods of 5 min or longer made the membrane uneven and/or increased the membrane resistance. By drying the polymer solution before quenching, the porous structure near the membrane surface was altered so that the membrane retains the bacterial cells. The membrane retained bacterial cells in the manner of a screen filter. The membranes developed in this research will be useful as a pre-filter in biochemical processes to enhance the life time of the final filters and to reduce industrial wastes due to being made of a compostable polymer.