Changes in cerebral hemoglobin concentration and oxygen saturation immediately after birth in the human neonate using full-spectrum near infrared spectroscopy
Changes in cerebral hemoglobin concentration and oxygen saturation immediately after birth in the human neonate using full-spectrum near infrared spectroscopy
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DOI：
10.1117/1.429997
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发表时间：
2000-07-01
影响因子：
3.5
通讯作者：
Onishi, S
中科院分区：
文献类型：
--
作者：
Isobe, K;Kusaka, T;Onishi, S
利用全光谱近红外光谱（fsNIRS），我们测量了7名新生儿出生后脑组织中氧和脱氧血红蛋白（HbO(2)和Hb）、总血红蛋白（T-Hb）浓度和血红蛋白氧饱和度（SbO2）的变化。发现HbO(2)在出生后2 ~ 3 min内迅速升高。与此同时，T-Hb浓度有一过性升高，随后随Hb一起下降。SbO2在出生后迅速增加，从1.5 min时的18%增加到5-6 min时的约55%，随后逐渐增加约10%。三名受试者在出生后立即短时间吸氧，其大脑的氧合作用比那些没有吸氧的人发生得快得多。这项初步研究表明，脑循环和氧合的动态变化是出生后不久发生的生理变化的一部分。(C) 2000光学仪器工程师学会。[s1083 - 3668(00) 00203 - 3]。
Using full-spectrum near infrared spectroscopy (fsNIRS), we measured changes in oxy- and deoxyhemoglobin (HbO(2) and Hb), total hemoglobin (T-Hb) concentration, and hemoglobin oxygen saturation (SbO2) in the brain tissue of seven neonates immediately following birth. It was found that HbO(2) rose rapidly within 2-3 min after birth. During the same time, there was a transient increase in T-Hb concentration, after which it decreased together with Hb. SbO2 increased rapidly after birth, from 18% at 1.5 min to about 55% at 5-6 min, followed by a gradual increase of about 10%. Oxygenation in the brain occurred much sooner in three subjects given oxygen for a short time immediately after birth than in those who did not receive oxygen. This preliminary study indicated that dynamic changes occur in cerebral circulation and oxygenation as part of the physiological changes taking place soon after birth. (C) 2000 Society of Photo-Optical Instrumentation Engineers. [S1083-3668(00)00203-3].