A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study
A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study
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DOI：
10.1093/ije/dyg264
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发表时间：
2003-12-01
影响因子：
7.7
通讯作者：
Freedman, LS
中科院分区：
文献类型：
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作者：
Schatzkin, A;Kipnis, V;Freedman, LS
大多数大型队列研究都使用食物频率问卷（FFQ）来评估饮食摄入量。然而，一些生物标志物研究对FFQ是否有足够的精度来检测适度但重要的饮食-疾病关联提出了质疑。我们使用观察蛋白质和能量营养（OPEN）研究的数据来比较FFQ和24小时回忆（24HR）的表现。OPEN研究包括来自马里兰州蒙哥马利县的484名健康志愿者（男性261名，女性223名），年龄在40-69岁之间。每位参与者被要求间隔3个月两次完成FFQ和24HR，并在第一次FFQ和24HR评估后的2周内进行双标记水（DLW）评估和两次24小时尿液收集。对于FFQ和24HR，以及男性和女性，我们计算了绝对能量、绝对蛋白质和蛋白质密度的衰减因子。结果对于绝对能量和蛋白质，单个FFQ的衰减因子为0.04 ~ 0.16。重复用药改善甚微（0.08-0.19）。单个24HR的衰减因子为0.10-0.20，但重复4次会产生0.20-0.37的衰减。对于蛋白质密度，单个FFQ的衰减为0.3-0.4；对于单个24HR，衰减系数为0.15-0.25，但在4次重复时衰减系数将增加到0.35-0.50。结论：由于严重的衰减，FFQ不能被推荐作为评估能量或蛋白质绝对摄入量与疾病之间关系的工具。虽然这种衰减在能量调节蛋白的分析中有所减少，但对于FFQ和多个24HR来说仍然是实质性的。这些工具中的任何一种用于检测重要但中等的相对风险（在1.5和2.0之间）的效用，甚至对于能量调整饮食因素，都是值得怀疑的。
Background Most large cohort studies have used a food frequency questionnaire (FFQ) for assessing dietary intake. Several biomarker studies, however, have cast doubt on whether the FFQ has sufficient precision to allow detection of moderate but important diet-disease associations. We use data from the Observing Protein and Energy Nutrition (OPEN) study to compare the performance of a FFQ with that of a 24-hour recall (24HR).Methods The OPEN study included 484 healthy volunteer participants (261 men, 223 women) from Montgomery County, Maryland, aged 40-69. Each participant was asked to complete a FFQ and 24HR on two occasions 3 months apart, and a doubly labelled water (DLW) assessment and two 24-hour urine collections during the 2 weeks after the first FFQ and 24HR assessment. For both the FFQ and 24HR and for both men and women, we calculated attenuation factors for absolute energy, absolute protein, and protein density.Results For absolute energy and protein, a single FFQ's attenuation factor is 0.04-0.16. Repeat administrations lead to little improvement (0.08-0.19). Attenuation factors for a single 24HR are 0.10-0.20, but four repeats would yield attenuations of 0.20-0.37. For protein density a single FFQ has an attenuation of 0.3-0.4; for a single 24HR the attenuation factor is 0.15-0.25 but would increase to 0.35-0.50 with four repeats.Conclusions Because of severe attenuation, the FFQ cannot be recommended as an instrument for evaluating relations between absolute intake of energy or protein and disease. Although this attenuation is lessened in analyses of energy-adjusted protein, it remains substantial for both FFQ and multiple 24HR. The utility of either of these instruments for detecting important but moderate relative risks (between 1.5 and 2.0), even for energy-adjusted dietary factors, is questionable.