Sensitivity and specificity of the Mini-Mental State Examination for identifying dementia in the oldest-old: The 90+study
Sensitivity and specificity of the Mini-Mental State Examination for identifying dementia in the oldest-old: The 90+study
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DOI：
10.1111/j.1532-5415.2007.01049.x
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发表时间：
2007-02-01
影响因子：
6.3
通讯作者：
Kawas, Claudia H.
中科院分区：
文献类型：
--
作者：
Kahle-Wrobleski, Kristin;Corrada, Maria M.;Kawas, Claudia H.
目的：评价迷你精神状态检查（MMSE）在年龄和教育程度分层时识别老年痴呆的敏感性和特异性。设计:横断面。设置：研究、诊所和家访。参与者：以人群为基础的90岁及以上的成年人样本（n=435），他们参加了90+研究，这是一项纵向的、以人群为基础的研究。测量：神经学检查以确定痴呆诊断、MMSE和人口统计数据。结果：受试者工作特征（ROC）分析表明，MMSE对不同年龄和教育程度的90岁及以上受试者的痴呆诊断准确率较高（ROC曲线下面积为0.82 ~ 0.98）。对于以下年龄组：90-93、94-96和>= 97，给出了可能的截止值范围和相应的敏感性和特异性。各年龄组别按受教育程度细分(
OBJECTIVES: To evaluate the sensitivity and specificity of the Mini-Mental State Examination (MMSE) in identifying dementia in the oldest-old when stratified by age and education.DESIGN: Cross-sectional.SETTING: Research clinic and in-home visits.PARTICIPANTS: Population-based sample of adults aged 90 and older (n=435) who are enrolled in the 90+ Study, a longitudinal, population-based study. MEASUREMENTS: Neurological examination to determine dementia diagnosis, MMSE, and demographic data.RESULTS: Receiver operating characteristic (ROC) analyses indicated that the MMSE had high diagnostic accuracy for identifying dementia in subjects aged 90 and older across different age and education groups (area under the ROC curve values ranged from 0.82 to 0.98). A range of possible cutoff values and corresponding sensitivity and specificity are provided for the following age groups: 90-93, 94-96, and >= 97. Age groups were subdivided by educational attainment (