Antiserum to somatostatin prevents stress-induced inhibition of growth hormone secretion in the rat.

Antiserum to somatostatin prevents stress-induced inhibition of growth hormone secretion in the rat.
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生长抑素抗血清可防止应激引起的大鼠生长激素分泌抑制。

DOI:
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发表时间:
1976
期刊:
影响因子:
56.9
通讯作者:
Y. Patel
Y. Patel
中科院分区:
综合性期刊1区
文献类型:
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作者:
L. C. Terry;John O. Willoughby;John O. Willoughby;P. Braseau;Joseph B. Martin;Y. Patel

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血浆生长激素水平下降,并在大鼠应激后几个小时内保持低水平。当抗血清生长抑素给予大鼠应激前,生长激素分泌脉冲部分恢复。结果提供证据表明,循环生长抑素在应激诱导的生长激素分泌抑制中起着重要作用。
Plasma growth hormone levels fall and remain low for several hours after stress in the rat. When antiserums to somatostatin are administered to rats prior to stress, growth hormone secretory pulses are partially restored. The results provide evidence that circulating somatostatin plays a prominent role in stress-induced inhibition of growth hormone secretion in the rat.