Two-Photon Near Infrared Fluorescent Turn-On Probe Toward Cysteine and Its Imaging Applications
Two-Photon Near Infrared Fluorescent Turn-On Probe Toward Cysteine and Its Imaging Applications
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DOI:
10.1021/acssensors.5b00271
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发表时间:
2016-07-01
期刊:
影响因子:
8.9
通讯作者:
Dong, Yizhou
中科院分区:
文献类型:
--
作者:
Wang, Junfeng;Li, Bin;Dong, Yizhou
Two-photon excitable (850 nm) NIR fluorescent turn-on (702 nm) probe TP-NIR was synthesized for selective detection of cysteine (Cys). The probe itself shows is turned on by reaction with Cys in aqueous buffer. In addition, the probe displays greater selectivity for Cys over other thiols, including glutathione (GSH) and homocysteine (Hcy). Moreover, the large Stokes shift, NIR excitation, and NIR emission make this probe suitable for biological imaging.