Snapshot hyperspectral retinal camera with the Image Mapping Spectrometer (IMS).
Snapshot hyperspectral retinal camera with the Image Mapping Spectrometer (IMS).
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DOI：
10.1364/boe.3.000048
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发表时间：
2012-01-01
影响因子：
3.4
通讯作者：
Tkaczyk TS
中科院分区：
文献类型：
--
作者：
Gao L;Smith RT;Tkaczyk TS
我们提出了一个快照高光谱视网膜相机与图像映射光谱仪（IMS）的眼睛成像应用。所得到的系统能够以5.2 fps的帧速率同时采集470 nm-650 nm范围内的48个光谱通道图像。每个测量光谱场景的空间采样为350 × 350像素。这种快照设备的优点是消除了传统的基于扫描的高光谱视网膜相机中的眼睛运动伪影和像素配准不良问题，以及具有亚秒时间分辨率的氧饱和度动态的实时成像。光谱成像性能在活体人类视网膜成像实验中得到证明。利用该装置成功获取了氧合血红蛋白和黄斑色素的吸收光谱特征。
We present a snapshot hyperspectral retinal camera with the Image Mapping Spectrometer (IMS) for eye imaging applications. The resulting system is capable of simultaneously acquiring 48 spectral channel images in the range 470 nm–650 nm with frame rate at 5.2 fps. The spatial sampling of each measured spectral scene is 350 × 350 pixels. The advantages of this snapshot device are elimination of the eye motion artifacts and pixel misregistration problems in traditional scanning-based hyperspectral retinal cameras, and real-time imaging of oxygen saturation dynamics with sub-second temporal resolution. The spectral imaging performance is demonstrated in a human retinal imaging experiment in vivo. The absorption spectral signatures of oxy-hemoglobin and macular pigments were successfully acquired by using this device.