Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life
Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life
复制标题
DOI：
10.1111/joor.12019
复制
发表时间：
2013-03-01
影响因子：
2.9
通讯作者：
Verin, E.
中科院分区：
文献类型：
--
作者：
Paris, G.;Martinaud, O.;Verin, E.
吞咽困难是肌萎缩侧索硬化症（ALS）最重要的并发症之一。我们的目的是确定口咽吞咽困难是否影响ALS患者的生活质量（QoL）。招募了30名连续患者（3182岁，18名男性）。吞咽功能评价使用标准化的电视透视钡吞咽。所有患者在视频透视后立即完成吞咽困难生活质量（SWAL-QoL）的特定问卷。吞咽困难严重程度量表的结果将14例口咽吞咽困难患者和16例吞咽功能正常的患者分开。两组的平均年龄、体重和体重指数无差异（吞咽困难患者：68 +/-11 kg，非吞咽困难患者：69 +/-14 kg）。根据Norris评分（20 ± 8分），吞咽困难患者中以延髓受累者居多，明显低于非吞咽困难患者（35 ± 5分）（P
Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (3182years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL-QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 +/- 11kg versus non-dysphagic patients: 69 +/- 14kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 +/- 8), significantly lower than those of the non-dysphagic patients (35 +/- 5) (P